ACM BCB 2011 Program
Sunday, July 31, 2011
1:00pm-5:00pm Registration in Lakeshore Ballroom prefunct
Monday, Aug. 1, 2011
7:30am-8:30am Registration and Continental Breakfast
Location: Lakeshore Ballroom prefunct
8:30am-5:00pm WORKSHOPS & TUTORIALS
Workshop 1 in Lakeshore Ballroom A
Workshop 2 in Lakeshore Ballroom B
Workshop 3 in Lakeshore Ballroom C
LINCOLN PARK ROOM
Workshop 4, 8:30-Noon
Tutorial, 1:30-3:00pm
- Knowledge Discovery in Academic-Based Drug Design: New Opportunities and Challenges (Jun Luke Juan, Univ. of Kansas)
Tutorial, 3:30-5:00pm
-Topological Indexing and Mining of Chemical Compounds (Sayan Ranu and Ambuj Singh, UC-Santa Barbara)
10:00am-10:30am Morning Break
Noon-1:30pm Lunch on your own
3:00pm-3:30pm Afternoon Break
6:00pm-8:00pm Workshop/Tutorial only poster session
Tuesday, Aug. 2, 2011
7:30am-8:45am Registration and Continental Breakfast
Location: Lakeshore Ballroom prefunct
8:45am-10:00am Keynote talk
Michael Jordan from the University of California at Berkeley will give a keynote on “Statistical Inference of Protein Structure and Function”
Location: Lakeshore Ballroom
10:00am-10:30am Morning Break
10:30am-Noon PAPER SESSIONS
PAPER SESSION 1 Biological Networks (Regular papers; LAKESHORE A)
Session chair: Xinghuan Lu, University of Pittsburgh
- “Knowledge-Guided Differential Dependency Network Learning for Detecting Structural Changes in Biological Networks,” Ye Tian*, Virginia Tech; Bai Zhang, Virginia Tech; Ie-Ming Shih, Johns Hopkins University; Yue Wang, Virginia Tech
- “A Novel Framework for Large Scale Metabolic Network Alignments by Compression,” Michael Dang, University of Florida; Ferhat Ay*, University of Florida; Tamer Kahveci, University of Florida
- “Scalable Multiple Global Network Alignment for Biological Data,” Yu-Keng Shih*, Ohio State University; Srinivasan Parthasarathy, Ohio State University
PAPER SESSION 2 Proteins and gene expression (Short papers; LAKESHORE B)
Session chair: Chris Bailey-Kellogg, Dartmouth
- “An efficient algorithm for matching protein binding sites for protein function prediction,” Leif Ellingson, Florida State University; Jinfeng Zhang, Florida State University
- “Improving Protein Flexibility Predictions by Combining Statistical Sampling with a Mean-Field Virtual Pebble Game,” Luis Gonzalez, UNC-Charlotte; Dennis Livesay, UNC-Charlotte; Donald Jacobs, UNC-Charlotte
- “Kernel Methods for Calmodulin Binding and Binding Site Prediction,” Asa Ben-Hur, Colorado State University; Michael Hamilton, Colorado State University; Anireddy S.N. Reddy, Colorado State University
- “Inferring Conflict-Sensitive Phosphorylation Dynamics,” Qiong Cheng, University of Miami; Mitsunori Ogihara, University of Miami; Vineet Gupta, University of Miami
- “Changes in gene expression near evolutionary breakpoints,” David Sankoff, Department of Mathematics and Statistics University of Ottawa; Adriana Muñoz, University of Ottawa
PAPER SESSION 3 Proteins (Regular papers; LAKESHORE C)
Session chair: Gultekin Ozsoyoglu, Case Western Reserve University
- “Probabilistic Ensembles for Improved Inference in Protein-Structure Determination,” Ameet Soni*, University of Wisconsin-Madison; Jude Shavlik , University of Wisconsin-Madison
- “Parallel Simulation of Multiple Proteins Through a Bioreactor Coupled with Biochemical Reactions,” Changjiang Zhang*, University of Kentucky; Kimberly Forsten-Williams, Virginia Tech; Michael Fannon, University of Kentucky; Wensheng Shen, SUNY Brockport; Jun Zhang, University of Kentucky
- “Multi-view prediction of protein function,” Artem Sokolov*, Colorado State University; Asa Ben-Hur, Colorado State University
POSTER PAPER SESSION I (LINCOLN PARK)
Session chair: Sun Kim, Indiana University
Noon-1:30pm Lunch on your own
1:30pm-3:00pm PAPER SESSIONS
PAPER SESSION 4 Interactions and Pathways (Regular papers; LAKESHORE A)
Session chair: Tamer Kahveci, University of Florida
- “FUSE: Towards Multi-Level Functional Summarization of Protein Interaction Networks,” Boon-Siew Seah, Nanyang Technological Univ; Sourav S Bhowmick*, Nanyang Technological Univ; C Forbes Dewey, Jr, MIT, USA; Hanry Yu, National University of Singapore
- “Similarity Boosting for Label Noise Tolerance in Protein-Chemical Interaction Prediction,” Aaron Smalter Hall*, University of Kansas; Jun Huan, University of Kansas; Gerald Lushington, University of Kansas
- “Sensitive Detection of Pathway Perturbations in Cancers,” Corban Rivera, Johns Hopkins University; Brett Tyler, Virginia Tech; T. M. Murali*, Virginia Tech
PAPER SESSION 5 Sequence Analysis (Short papers; LAKESHORE B)
Session chair: Chandan Reddy, Wayne State University
- “Formatt: Correcting Protein Multiple Structural Alignments by Sequence Peeking,” Shilpa Nadimpalli, Tufts University; Noah Daniels, Tufts University; Lenore Cowen, Tufts University
- “DynMap : mapping short reads to multiple related genomes,” Solon Pissis, King’s College London; Tomas Flouri, CTU; Costas Iliopoulos, King’s College London
- “Detection of Novel Tandem Duplication with Next-Generation Sequencing,” Thomas K.F. Wong, The University of Hong Kong; Xuan Liu, The University of Hong Kong; Shing-Wan Choi, The University of Hong Kong; Tak-Wah Lam, The University of Hong Kong; Siu Ming Yiu, The University of Hong Kong
- “Mapping Short Sequencing Reads to Distant Relatives,” Vinicio Reynoso, Loyola University Chicago; Catherine Putonti, Loyola University Chicago
- “TreeLign: Simultaneous Stepwise Alignment and Phylogenetic Positioning, with its Application to Automatic Phylogenetic Assignment of 16S rRNAs,” Shaojie Zhang , University of Central Florida; Yuan Li, University of Central Florida; Aaron Halpern, Complete Genomics
PAPER SESSION 6 Computational Structural Biology (Regular papers; LAKESHORE C)
Session chair: Luke Huan, University of Kansas
- “Predicting Folding Pathways between RNA Conformational Structures Guided by RNA Stacks,” Shaojie Zhang *, University of Central Florida; Yuan Li, University of Central Florida
- “Improved Machine Learning Models for Predicting Selective Compounds,” Xia Ning*, UMN; George Karypis, University of Minnesota
- “Combining Ambiguous Chemical Shift Mapping with Structure-Based Backbone and NOE Assignment from 15N-NOESY,” Richard Jang*, University of Waterloo; Xin Gao, King Abdullah University of Science and Technology; Ming Li, University of Waterloo
POSTER PAPER SESSION II (LINCOLN PARK)
Session chair: Jie Liang, University of Illinois at Chicago
3:00pm-3:30pm Afternoon Break
3:30pm -5:00pm PAPER SESSIONS
PAPER SESSION 7 Network Analysis (Regular papers; LAKESHORE A)
Session chair: Osmar Zaiane, Simon Fraser University
- “Neural System Modeling and Simulation using Hybrid Functional Petri Net,” Yin Tang*, Fudan University; Fei Wang, Fudan University
- “Mathematical Network Model for Bone Mineral Density (BMD) and Bone Quality Assessment,” Taehyong Kim*, SUNY at Buffalo
- “An integrative approach to infer regulation programs in a transcription regulatory module network,” Jianlong Qi*, Concordia University; Tom Michoel, Freiburg Institute for Advanced Studies; Gregory Butler, Concordia University
PAPER SESSION 8 Protein Interaction Networks (Short papers; LAKESHORE B)
Session chair: Asa Ben-Hur, Colorado State University
- “Modeling of Multi Domain Contribution to Protein Interaction,” Woo-Hyuk Jang, KAIST; Suk-Hoon Jung, KAIST; Bo-Ra Hyun, KAIST ; Dong-Soo Han , KAIST
- “A fuzzy entropy based approach for development of Gene Prediction Networks (GPNs): Detecting altered dependency in carcinogenic state,” Anupam Ghosh, Netaji Subhash Engineering Col; Rajat De, Indian Statistical Institute
- “An ACO Based Functional Module Detection Algorithm For Protein Interaction Network,” Lei Shi, SUNY at Buffalo
- “A Statistical Approach for Extracting Protein-Protein Interactions,” Lindsey Bell, Florida State University; Jinfeng Zhang, Florida State University; Xufeng Niu, Florida State University
- “Sequence Based Partner-Specific Prediction of Protein- Protein Interfaces and its Application in Ranking Docked Models,” Li Xue, Iowa State University; Rafael Jordan, Iowa State University; Yasser EL-Manzalawy , Iowa State University; Drena Dobbs, Iowa State University; Vasant Honavar, Iowa State University
PAPER SESSION 9 Evolution and Phylogeny (Regular papers; LAKESHORE C)
Session chair: Dannie Durand, CMU
- “Inference of tumor phylogenies from genomic assays on heterogeneous samples,” Ayshwarya Subramanian, Carnegie Mellon University; Russell Schwartz*, Carnegie Mellon University; Stanley Shackney, Carnegie Mellon University
- “Using Compact Encodings for Path-based Computations on Pedigree Graphs,” Lei Yang, Case Western Reserve University; En Cheng, ; Meral Ozsoyoglu*, CWRU
- “A Two-Way Multi-dimensional Mixture Model for Clustering Metagenomic Sequences,” Shruthi Prabhakara*, Pennsylvania State University; Raj Acharya, Pennsylvania State University
PAPER SESSION 10 Computational Systems Biology (Short papers; LINCOLN PARK)
Session chair: Vasant Honavar, Iowa State University
- “PANI: A Novel Algorithm for Fast Discovery of Putative Target Nodes in Signaling Networks,” Huey-Eng Chua, Nanyang Technological Univ; Sourav S Bhowmick, Nanyang Technological Univ; Qing Zhao, Nanyang Technological Univ; Lisa Tucker-Kellogg, National University of Singapore; C Forbes Dewey, Jr, MIT, USA; Hanry Yu, National University of Singapore
- “A scalable Approach for Inferring Transcriptional Regulation in the Yeast Cell Cycle,” Akther Shermin, Macquarie University; Hasan Jamil, Wayne State University; Mehmet Orgun, Macquarie University
- “Ranking Differential Genes in Co-expression Networks,” Omar Odibat, Wayne State University; Chandan Reddy, Wayne State University
- “A graph model and an exact algorithm to find transcription factor modules,” Songjian Lu, University of Pittsburgh; Xinghua Lu, University of Pittsburgh
- “An ACO Based Functional Module Detection Algorithm For Protein Interaction Network,” Lei Shi, SUNY at Buffalo
6:00pm-8:00pm POSTER RECEPTION
Wednesday, Aug. 3, 2011
7:30am-8:45am Registration and Continental Breakfast
Location: Lakeshore Ballroom prefunct
8:45am-10:00am Keynote talk
Nancy Cox from the University of Chicago will give a keynote on “Transitions: GWAS to Sequencing, Discovery to Understanding, and Bench to Bedside.”
Location: Lakeshore Ballroom
10:00am-10:30am Morning Break
10:30am-Noon PAPER SESSIONS
PAPER SESSION 11 Alignment and Assembly (Regular papers; LAKESHORE A)
Session chair: Yufeng Wu, University of Connecticut
- “NcRNA Homology Search Using Hamming Distance Seeds,” Osama Aljawad, Michigan State University; Yanni Sun*, Michigan State University; Jikai Lei, Michigan State University; Alex Liu, Michigan State University
- “Detecting Fuzzy Amino Acid Tandem Repeats in Protein Sequences,” Marco Pellegrini*, IIT – CNR; M. Elena Renda, IIT – CNR; Alessio Vecchio, Dip. Ing. Inf. – Università di Pisa
- “MetaVelvet : An extension of Velvet assembler to de novo metagenome assembly from short sequence reads,” Toshiaki Namiki, Keio University; Tsuyoshi Hachiya, Keio University; Hideaki Tanaka, Keio University; Yasubumi Sakakibara*, Keio University
PAPER SESSION 12 Visualization and Image Analysis (Short papers; LAKESHORE B)
Session chair: Rajat Kumar De, Indian Statistical Institute
- “Dynamic Visualization and Comparative Analysis of Multiple Collinear Genomic Data,” Jeremy Wang, UNC; Leonard McMillan, University of North Carolina; Fernando Pardo-Manuel de Villena, University of North Carolina at Chapel Hill
- “Topology aware coloring of gene regulatory networks,” Gunhan Gulsoy, University of Florida; Bhavik Gandhi, University of Florida; Tamer Kahveci, University of Florida
- “Geometric Visualization of Transcription Factor Binding Sites in Context,” Chih Lee, University of Connecticut; Chun-Hsi Huang, University of Connecticut
- “Counting Cells in 3D Confocal Image for Fruitfly based on Discriminative Models,” Jie Zhou, Northern Illinois University
- “Classification and Interest Region Localization on Craniosynostosis Skulls,” Shulin Yang, Univ. of Washington; Linda Shapiro, Univ. of Washington ; Su-In Lee, Univ. of Washington; Michael Cunningham, Univ. of Washington; Matthew Speltz, Univ. of Washington
PAPER SESSION 13 Classification Models (Regular papers; LAKESHORE C)
Session chair: Aidong Zhang, State University of New York at Buffalo
- “Knowledge-based Bayesian network for the classification of Mycobacterium tuberculosis complex sublineages,” Minoo Aminian*, Rensselaer Polytechnic Institute; Kristin Bennett, Renesselaer Polytechnic Institute; Amina Shabbeer, Renesselaer Polytechnic Institute; Kane Hadley, Renesselaer Polytechnic Institute
- “Win Percentage for Comparing Classifiers under the Uncertainty of Feature Selection,” R. Mitchell Parry*, Georgia Tech / Emory; John Phan, Georgia Tech / Emory; May Wang, Georgia Tech
- “Classification of Breast Cancer Grades through Quantitative Characterization of Ductal Structure Morphology in Three-Dimensional Cultures,” Basak Oztan*, Rensselaer Polytechnic Inst.; Lindsey Polizzotti, Rensselaer Polytechnic Institute; Cemal Bilgin, RPI; Kira Henderson, Rensselaer Polytechnic Institute; George Plopper, Rensselaer Polytechnic Institute; Bulent Yener, Rensselaer Polytechnic Institute
PAPER SESSION 17 (Short papers; LINCOLN PARK)
Session chair: Jing Li, Case Western Reserve University
- “A tripartite clustering analysis on microRNA, gene and disease model,” Chengcheng Shen, Univ. of Texas at Dallas; Ying Liu, Univ. of North Texas at Dallas
- “A Bayesian Integration Model of Heterogeneous Data Sources for Improved Gene Functional Inference,” Noor Al Aydie, Wayne State University; Chandan Reddy, Wayne State University; Farshad Fotouhi, Wayne State University
- “Association between response to brief trastuzumab exposure in cell lines and early stage HER2+ breast tumors,” Emmett Sprecher, Yale Univ.; Steven Kleinstein, Yale University School of Medicine; Lyndsay Harris, Yale Univ.; David Tuck, Yale Univ.
- “A Novel K-mer Mixture Logistic Regression for Methylation Susceptibility Modeling of CpG Dinucleotides in Human Gene Promoters,” Youngik Yang, J. Craig Venter Institute
- “Resolving Observation Conflicts in Steady State Metabolic Network Dynamics Analysis ,” Ercument Cicek, Case Western Reserve Univ.; Tekin Ozsoyoglu, Case Western Reserve Univ.
Noon-1:30pm Lunch on your own
1:30pm-3:00pm PAPER SESSIONS
PAPER SESSION 14 Sequence Analysis (Regular papers; LAKESHORE A)
Session chair: Leonard McMillan, UNC Chapel Hill
- “Algorithms for optimizing cross-overs in DNA shuffling,” Lu He, Dartmouth Computer Science; Alan Friedman, Purdue Biological Sciences; Chris Bailey-Kellogg*, Dartmouth
- “Using Inversion Signatures to Generate Draft Genome Sequence Scaffolds,” Zanoni Dias*, UNICAMP and Virginia Tech; Ulisses Dias, Unicamp; João Setuba, Virginia Tech
- “A Fast Method for Large-scale Multichromosomal Breakpoint Median Problems,” Maryam Haghighi*, University of Ottawa; Sylvia Boyd, University of Ottawa
PAPER SESSION 15 Simulation and Data Analysis (Short papers; LAKESHORE B)
Session chair: Keun Ryu, Chungbuk National University
- “Sequence-Based Prediction of HIV-1 Coreceptor Usage: Utility of n-Grams for Representing gp120 V3 Loops,” Majid Masso, George Mason University
- “Generation of Synthetic Data and Design of Simulations in Evaluating Interactions for Association Studies,” Jing Li, Case Western Reserve University, Computer Science; Yixuan Chen, Case Western Reserve University
- “Computational Interpretation of Metabolomics Measurements: Steady-State Metabolic Network Dynamics Analysis,” Xinjian Qi, Case Western Reserve Univ.; Tekin Ozsoyoglu, Case Western Reserve Univ.; Ali Cakmak, Case Western Reserve Univ.; Ercument Cicek, Case Western Reserve Univ.
- “ISO: Numeric Representation of Nucleic Acid Forms,” M. Fanning, University of New Mexico; Joanne Macdonald, Columbia University; Darko Stefanovic, University of New Mexico
- “Erlang-Delayed Stochastic Chemical Kinetic Formalism for Efficient Analysis of Biological Systems with Non-elementary Reaction Effects,” Hiroyuki Kuwahara, Carnegie Mellon University; Chris Myers, University of Utah
PAPER SESSION 16 Microarrays and Beyond (Regular papers; LAKESHORE C)
Session chair: May Wang, Georgia Institute of Technology
- “Biological Assessment of Grid and Spot Detection in cDNA Microarray Images,” Iman Rezaeian, University of Windsor; Luis Rueda*, University of Windsor
- “Identifying pair-wise gene functional similarity by multiplex gene expression maps and supervised learning,” Li An*, Temple University; Haibin Ling, Center for Information Science and Technology, Temple University; Zoran Obradovic, Center for Information Science and Technology, Temple University; Desmond Smith, UCLA; Vasileios Megalooikonomou, Center for Information Science and Technology, Temple University
3:00pm-3:30pm Afternoon Break
3:30pm-4:15pm Annual SIG Business Meeting
4:15pm-5:00pm ACM Tech Pack Initiative
6:00pm-8:00pm ACM-BCB11 Conference & Award Ceremony Banquet