University at Buffalo
The State University of New York
CCR
Center for
Computational Research
Bioinformatics
nThe use of HPC to analyze data generated by the Human
Genome Project to improve medical
treatment.
nPrecise sequence of ~30K human genes have been
mapped
qCritical to
elucidate the function of each gene.
qLeads to
greater understanding of human development.
qPotential to treat many diseases, including
AIDS cancer, MS, and Alzheimer’s and provide personalized treatment.
nFrom Human Genome
qLocate genes (tens of thousands in human body)
qDetermine what protein a gene regulates (millions of
proteins in body)
qDetermine structure
qDetermine protein function
qDevise drugs to block or enhance protein function