University at Buffalo
The State University of New York
CCR
Center for
Computational Research
Bioinformatics
nThe
creation and development of advanced information and computational technologies to solve problems in
biology.
nThe
use of advanced computational resources and techniques to analyze data generated by the Human Genome Project to improve
medical treatment.
nPrecise
sequence of ~30K human genes have been mapped
qCritical to elucidate the function of each
gene.
qLeads to greater understanding of human
development.
qPotential to treat many diseases, including
AIDS cancer, MS, and Alzheimer’s and provide personalized treatment.
nFrom Human
Genome
qLocate genes
(tens of thousands in human body)
qDetermine
what protein a gene regulates (millions of proteins in body)
qDetermine
structure
qDetermine
protein function
qDevise drugs
to block or enhance protein function