University at Buffalo
The State University of New York
CCR
Center for
Computational Research
nInterferes with formation of bacterial walls
nLast line of defense against deadly
qstreptococcal and staphylococcal bacteria strains
nVancomycin resistance exists (Michigan)
nCan’t just synthesize variants and test
nNeed structure-based approach to predict
nSolution with SnB (Shake-and-Bake)
qPat Loll
qGeorge Sheldrick
Vancomycin