Bioinformatics
n The creation and development of advanced information and
computational technologies to solve problems in biology.
n The use of advanced computational resources and techniques to analyze
data generated by the Human Genome Project to improve medical
treatment.
n Precise sequence of ~30K human genes have been mapped
q Critical to elucidate the function of each gene.
q Leads to greater understanding of human development.
q Potential to treat many diseases, including AIDS cancer, MS, and Alzheimer’s
and provide personalized treatment.
n From Human Genome
q Locate genes (tens of thousands in human body)
q Determine what protein a gene regulates (millions of proteins in body)
q Determine structure
q Determine protein function
q Devise drugs to block or enhance protein function