Comments: hadar ContactPerson: huiluo@cse.buffalo.edu ### Begin Citation ### Do not delete this line ### %R 2001-07 %U /u0/csestaff/stock/dissertation.prn %A LUO, Hui %T KNOWLEDGE-BASED IMAGE UNDERSTANDING AND CLASSIFICATION SYSTEM FOR MEDICAL IMAGE DATABASES %D July 30, 2001 %I Department of Computer Science and Engineering, SUNY Buffalo %K Medical images databases, Knowledge-based, image understanding, image classification, feature extraction, snake model, object-oriented representation %X The understanding of medical images involves the identification of anatomical structures in images, the establishment of the relationships among the structures and the matching them with pre-defined anatomical models. The closer this match, the better the image is understood. Hence, the development and use of anatomical knowledge models are critical to the effectiveness of the system. In this thesis, we will present a new knowledge model for medical image content analysis based on the object-oriented paradigm. The new model abstracts common properties from different types of medical images by using three attributes: description, component, and semantic graph, and specifies its actions to schedule the detection procedure, properly deform the model shapes to match the corresponding anatomies in images, select the best match candidates, and verify the candidates¡¯ spatial relations with the semantic graph defined in the model. The advantage of the new model includes: 1) It presents a robust representation ability to represent the object variability, 2) It provides a tighter bond between features and methods, and 3) It supports the complex image analysis and works on both normal and abnormal images. Based on this model, a knowledge-based medical image classification system is developed. The system assigns each input image with one or more most similar models by performing a two-stage processing. The first stage, coarse shape classification, focuses on the global shape features of objects in the processed images. The second stage performs a detail matching between extracted image features and model specified properties. The output match results imply a set of models which are most possible to be existed in the processed image. To further confirm them, an evaluation strategy is used to reject those unreasonable results and inference the high confidence match models. To improve the detection accuracy, we also proposed a new region model which combines both region and edge information into image segmentation, and reformulate the traditional snake model and level set model with it. As expected, the reformulated models demonstrate robust ability to deal with the ambiguity in images and overcome the problem associated with the initialization. The performance of the system has been tested on different types of digital radiographs, including chest, pelvis, ankle, elbow and etc. The experimental results suggest that the system prototype is applicable and robust, and the accuracy of the system is nearly 70% in our image databases.