Please read the passage given below: it is an extract from a medical report.
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NUTLEY, N.J., March 19, 1997 -- Relief is now available for the anxiety many children suffer when undergoing difficult medical procedures or facing surgery. The U.S. Food and Drug Administration (FDA) granted marketing clearance today to a
for use in children.
The medication, Versed(R) (midazolam HCl), can be used to calm and sedate children who must undergo procedures such as bone-marrow aspiration or spinal tap. Sedating a child also may spare parents the trauma of watching their child being physically restrained during procedures. Without sedation, such restraint is often necessary, and parents may even participate in restraining their child, which can be very distressing.
Versed also can be used to help calm children facing surgery, who might otherwise be terrified by the mask used to administer anesthesia, or by separation from their parents.
Versed now is also available for use in infants and children of all ages in critical care settings. This is the first time a
has been approved for use of any kind in newborns. Without sedation, babies and children may have a difficult time tolerating a breathing tube or ventilator -- and "fighting" a ventilator can be life-threatening.
"FDA clearance of Versed reflects the increasing recognition that children feel as much pain and anxiety as adults, and should be offered the same level of relief," said Maureen Strafford, M.D., director of pediatric cardiac anesthesiology at the New England Medical Center in Boston. "Unfortunately, the
currently relied on most often for kids is the phrase 'almost done.'"
After sedation with Versed, a child usually has little or no memory of undergoing the procedure. This "amnestic" quality of Versed is particularly advantageous because without it, children sometimes suffer from nightmares or other psychological traumas after undergoing medical procedures.
Versed, marketed by Hoffmann-La Roche, has already been used safely in 24 million children worldwide, but today's marketing clearance of Versed for use in pediatrics now gives doctors specific dosing recommendations for administering the medication to children.
"Versed is a very important drug for children," said Charles Cote, M.D., professor of anesthesia at Northwestern University Medical School in Chicago. "I'm hoping that other pharmaceutical companies will follow Roche's lead in clarifying prescribing information for a drug widely used in children."
A variety of uses Versed is an injectable
that has a variety of uses, depending on its dosage and administration. It can be used as a light
to help alleviate a child's anxiety before a therapeutic or diagnostic procedure, as well as to allow the child to forget what happened during the period of sedation; as a mild to moderate
to cause a deeper state of sedation; and as a part of general anesthesia during surgery. Intravenous Versed also can be administered by continuous infusion to children in critical care settings.
Safety Versed was introduced for adult use in 1986. The medication works rapidly, providing sedation within five minutes, and is eliminated from the body quickly. Its availability for use in children was based on clinical experience with the drug in more than 24 million children worldwide.
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